COMPARISON OF COLOR FUNDUS PHOTOGRAPHS AND FUNDUS AUTOFLUORESCENCE IMAGES IN MEASURING GEOGRAPHIC ATROPHY AREA

Segmentation of the geographic atrophy in spectral-domain optical coherence tomography and fundus autofluorescence images.

PURPOSE Geographic atrophy (GA) is the atrophic late-stage manifestation of age-related macular degeneration (AMD), which may result in severe vision loss and blindness. The purpose of this study was to develop a reliable, effective approach for GA segmentation in both spectral-domain optical coherence tomography (SD-OCT) and fundus autofluorescence (FAF) images using a level set-based approach...

Registration of OCT fundus images with color fundus photographs based on blood vessel ridges

This paper proposes an algorithm to register OCT fundus images (OFIs) with color fundus photographs (CFPs). This makes it possible to correlate retinal features across the different imaging modalities. Blood vessel ridges are taken as features for registration. A specially defined distance, incorporating information of normal direction of blood vessel ridge pixels, is designed to calculate the ...

Abnormalities of Fundus Autofluorescence in Pigmented Paravenous Chorioretinal Atrophy

The aim of this study is to investigate fundus autofluorescence (FAF) as well as fluorescein angiography (FA), indocyanine green angiography (IA), and optical coherence tomography (OCT) in a patient with pigmented paravenous chorioretinal atrophy (PPCRA). A funduscopic examination revealed chorioretinal atrophy along the paravenous area in both eyes. A marked bone spicule pigment clumping toget...

Fundus autofluorescence patterns and optical coherence tomography in geographic atrophy secondary to AMD Authors:

Predictive value of fundus autofluorescence for development of geographic atrophy in age-related macular degeneration.

PURPOSE It has been suggested that lipofuscin accumulation, as measured by increased fundus autofluorescence (FAF), precedes progression or development of junctional zone geographic atrophy (GA) in age-related macular degeneration (AMD). The tools of biomedical image analysis were used to measure the probabilistic relationship of GA progression to increased FAF. METHODS Serial AF images of ei...